In JKDU we practice with simulated eye gouges, etc. in the training. The only way you will have time to apply this is if you are good at first defending the takedown. Even then, as Shirase pointed out, the person doing the takedown will often have his head in a position where it is difficult to get to the eyes. Again, practice against those takedowns so that you can rely on leverage and technique rather than pain compliance. Aloha!
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"If you want to learn how to fight, you must practice fighting against someone who is fighting back!" Burton Richardson
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