Technical terms like Cardiac glycocides are completely unknown to the primitive tribes but MAGIC would explain it well enough for them to know it's very powerfull indeed.
Cardiac glycosides are divided into two main types:
Bufadienolides are C24 steroids...
Cardenolides (most prevalent) are C23 steroids.
The primary cardiac glycoside present in Helleborus is the bufadienole,
hellebrin. Hellebrigenin, the
aglycone of hellebrin is more potent than the glycoside itself....POWERFULL MAGIC!!
Cardenolides have a hormonal nature as substances. Their effects are on the heart and kidney. Cardenolides are classified according to the chemical composition of their aglycones as
lanataglucosides. (A,B,C,D and E)There is only one plant known to have all five and every part of it is toxic.
The assumed mechanism of action: inhibition of the Na+, K+-ATPase resulting in increased intracellular sodium and subsequent intracellular calcium leading to enhanced muscle contraction in cardiac tissue.
Just like
magic!!
http://www.ansci.cornell.edu/plants/...diacglyco.html