I have seen some medical info regarding hand conditioning and arthritis.
As for blood clots. If you were to sustain a large bruise it is possible that clotted blood from that bruise can enter the blood stream and go the lung or brain and lead to strokes or death. This goes for all large bruises and is not specific to bruises sustained in conditioning.
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eXcessiveFORCE.
If you must use force, make it excessive.
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