The problem with pressure point stuff is that in a real street combat situation where you feel threatened your body loses all capacity for fine movements, and instead falls back to large motor movements. You would never be able to execute these when it matters because your body would completely forget about them. As I understand it that is the principle that is behind self defense arts such as Krav Maga (I've never trained in that, though, only read about it).
I'm sure that pressure points do induce a lot of pain, and may well be able to be hit while sparring in the dojo, but I seriously doubt their real life effectiveness.
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