From a biological point of view pressure points exist in the form of nerve bundling inand around your body (Such as the Bracheal Plexus through the should and arm - would welcome corrections)...
They are useful things to know, but like any technique you need to know when to use them, trying to hit them won't work generally for the average fight because you lose fine motor control when the adrenalin kicks in... however going for the main targets will improve your chances of success say in a drawn out bout in the ring or in a 'gentlemans street agreement'
Some areas are the centre top of the thigh (hit it really hard with your elbow or a pointy thing and the whole leg will deaden), inbetween the bicep and tricep on the inner arm (corrections! If you hit that really hard say with a punch or knife hand and seperate the muscles the whole arm will deaden and the shock can knock them out) the same goes for the arm pit (right in) and the ribs just below the armpit...
also, if you have a greasy pole handy, a quick deep unexpected insertion up the anus will cause a blackout (seen this in a nursing home with a suppository, ew)
If you hit a quick succession of these points quickly then you will overwhelm the nervous system and cause a blackout... however unless you are well practised then best stay to the main pressure points we all use, jaw, temple, solar plexus and groin...
oh and in addition, don't try it if thier wearing anything thicker than a shirt or more than one layer...
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